Expression of RUFY4 in cancer - Summary - The Human Protein Atlas

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RUFY4

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RUFY4
Gene description	RUN and FYVE domain containing 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (Karpas-707)
HPA (normal tissue):	Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA037980
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037980

GENE INFORMATION
Gene name	RUFY4 (HGNC Symbol)
Synonyms	FLJ46536, ZFYVE31
Description	RUN and FYVE domain containing 4 (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q35
Chromosome location (bp)	218034960 - 218090581
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188282 (version 83.38)
Entrez gene	285180
UniProt	Q6ZNE9 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZNE9
Antibodypedia	RUFY4 antibodies

PROTEIN BROWSER

RUFY4-002	RUFY4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RUFY4-002 ENSP00000363270 ENST00000374155	C9J235 [Direct mapping] RUN and FYVE domain-containing protein 4 Show all	Predicted intracellular proteins Show all		607 aa 68.3 kDa	No	0
RUFY4-201 ENSP00000345900 ENST00000344321	Q6ZNE9 [Direct mapping] RUN and FYVE domain-containing protein 4 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0046872 [metal ion binding] Show all	571 aa 64.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.