Expression of IGFL1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

IGFL1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	IGFL1
Gene description	IGF-like family member 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (cervical cancer, head and neck cancer, melanoma, urothelial cancer)
HPA (cell line):	Group enriched (HaCaT, RT4, SK-BR-3)
HPA (normal tissue):	Tissue enriched (esophagus)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA014001
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (cervical cancer, head and neck cancer, melanoma, urothelial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA014001

GENE INFORMATION
Gene name	IGFL1 (HGNC Symbol)
Synonyms	UNQ644
Description	IGF-like family member 1 (HGNC Symbol)
Entrez gene summary	IGFL1 belongs to the insulin-like growth factor (IGF; see MIM 147440) family of signaling molecules that play critical roles in cellular energy metabolism and in growth and development, especially prenatal growth (Emtage et al., 2006 [PubMed 16890402]).[supplied by OMIM, Mar 2008]
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	46229752 - 46231243
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188293 (version 83.38)
Entrez gene	374918
UniProt	Q6UW32 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UW32
Antibodypedia	IGFL1 antibodies

PROTEIN BROWSER

IGFL1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IGFL1-001 ENSP00000415823 ENST00000437936	Q6UW32 [Direct mapping] Insulin growth factor-like family member 1 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005615 [extracellular space] Show all	110 aa 12.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.