Expression of C3orf62 in cancer - Summary - The Human Protein Atlas

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C3orf62

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	C3orf62
Gene description	Chromosome 3 open reading frame 62
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression in glandular cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA043328 , HPA053340
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PROGNOSTIC SUMMARY
Prognostic marker in urothelial cancer (favourable), stomach cancer (favourable), breast cancer (favourable), liver cancer (unfavourable), pancreatic cancer (favourable), lung cancer (favourable) and head and neck cancer (favourable).
Urothelial cancer p<0.001 Stomach cancer p<0.001 Breast cancer p<0.001 Liver cancer p<0.001 Pancreatic cancer p<0.001 Lung cancer p<0.001 Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043328	HPA053340

GENE INFORMATION
Gene name	C3orf62 (HGNC Symbol)
Synonyms	FLJ43654
Description	Chromosome 3 open reading frame 62 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p21.31
Chromosome location (bp)	49268602 - 49277909
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188315 (version 83.38)
Entrez gene	375341
UniProt	Q6ZUJ4 (UniProt - Evidence at protein level)
neXtProt	NX_Q6ZUJ4
Antibodypedia	C3orf62 antibodies

PROTEIN BROWSER

C3orf62-001	C3orf62-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
C3orf62-001 ENSP00000341139 ENST00000343010	Q6ZUJ4 [Direct mapping] Uncharacterized protein C3orf62 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	267 aa 30.2 kDa	No	0
C3orf62-004 ENSP00000413663 ENST00000436325	C9JW57 [Direct mapping] Uncharacterized protein C3orf62 Show all	Predicted intracellular proteins Show all		190 aa 21.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.