Expression of FAM83G in cancer - Summary - The Human Protein Atlas

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FAM83G

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM83G
Gene description	Family with sequence similarity 83, member G
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, most abundant in squamous epithelia.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA023369 , HPA023940
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PROGNOSTIC SUMMARY
Prognostic marker in stomach cancer (favourable) and liver cancer (unfavourable).
Stomach cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023369	HPA023940

GENE INFORMATION
Gene name	FAM83G (HGNC Symbol)
Synonyms	FLJ41564, PAWS1
Description	Family with sequence similarity 83, member G (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p11.2
Chromosome location (bp)	18968789 - 19004804
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188522 (version 83.38)
Entrez gene	644815
UniProt	A6ND36 (UniProt - Evidence at protein level)
neXtProt	NX_A6ND36
Antibodypedia	FAM83G antibodies

PROTEIN BROWSER

FAM83G-002	FAM83G-003	FAM83G-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM83G-002 ENSP00000373647 ENST00000388995	A6ND36 [Direct mapping] Protein FAM83G Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0030509 [BMP signaling pathway] Show all	823 aa 90.8 kDa	No	0
FAM83G-003 ENSP00000465602 ENST00000580115	K7EKG0 [Direct mapping] Protein FAM83G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		142 aa 15.4 kDa	No	0
FAM83G-201 ENSP00000343279 ENST00000345041	A6ND36 [Direct mapping] Protein FAM83G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005829 [cytosol] GO:0030509 [BMP signaling pathway] Show all	823 aa 90.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.