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CLN3

GENERAL INFORMATION

Gene name

 CLN3

Gene description

 Ceroid-lipofuscinosis, neuronal 3

Protein class

 Disease related genes
Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

 Intracellular,Membrane

Number of transcripts

 18
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in a number of tissues, most prominent in smooth muscle.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA063280
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Smooth muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 CLN3 (HGNC Symbol)

Synonyms

 BTS, JNCL

Description

 Ceroid-lipofuscinosis, neuronal 3 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 16

Cytoband

 p12.1

Chromosome location (bp)

 28477279 - 28495575

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000188603 (version 83.38)

Entrez gene

 1201

UniProt

 Q13286 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13286

Antibodypedia

 CLN3 antibodies

PROTEIN BROWSER
«
CLN3-001
CLN3-005
CLN3-006
CLN3-007
CLN3-008
CLN3-009
CLN3-012
CLN3-014
CLN3-017
CLN3-020
CLN3-027
CLN3-030
CLN3-031
CLN3-201
CLN3-202
CLN3-203
CLN3-204
CLN3-205
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CLN3-001
ENSP00000454229
ENST00000569430
Q13286 [Direct mapping]
Battenin
A0A024QZB8 [Target identity:100%; Query identity:100%]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 438 aa
47.6 kDa 		No 9
CLN3-005
ENSP00000455387
ENST00000567963
H3BPM8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 341 aa
36.3 kDa 		No 6
CLN3-006
ENSP00000329171
ENST00000333496
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 414 aa
45.2 kDa 		No 9
CLN3-007
ENSP00000379014
ENST00000395653
B4DMY6 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 338 aa
37 kDa 		No 8
CLN3-008
ENSP00000350457
ENST00000357806
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 339 aa
38 kDa 		No 6
CLN3-009
ENSP00000455603
ENST00000568558
H3BQ48 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 184 aa
20.7 kDa 		No 1
CLN3-012
ENSP00000350523
ENST00000357857
B4DFF3 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 384 aa
41.6 kDa 		No 8
CLN3-014
ENSP00000458015
ENST00000565778
O95090 [Direct mapping]
Battenin
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
Show all
 167 aa
18.5 kDa 		No 0
CLN3-017
ENSP00000454899
ENST00000568443
H3BNK7 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
Show all
 175 aa
18.9 kDa 		No 2
CLN3-020
ENSP00000456117
ENST00000565316
Q13286 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   8TM proteins predicted by MDM
Disease related genes
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 421 aa
45.6 kDa 		No 8
CLN3-027
ENSP00000455365
ENST00000567804
H3BPL0 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 74 aa
8.2 kDa 		No 1
CLN3-030
ENSP00000456122
ENST00000565688
H3BR84 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   4TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 176 aa
18.3 kDa 		No 4
CLN3-031
ENSP00000457615
ENST00000561505
H3BUF8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 121 aa
12.5 kDa 		No 3
CLN3-201
ENSP00000347660
ENST00000355477
Q9UBD8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 181 aa
19.3 kDa 		No 3
CLN3-202
ENSP00000353073
ENST00000359984
O95086 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   7TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 336 aa
36.8 kDa 		No 7
CLN3-203
ENSP00000353116
ENST00000360019
Q13286 [Direct mapping]
Battenin
A0A024QZB8 [Target identity:100%; Query identity:100%]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Disease related genes
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0001508 [action potential]
GO:0001575 [globoside metabolic process]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005764 [lysosome]
GO:0005765 [lysosomal membrane]
GO:0005769 [early endosome]
GO:0005770 [late endosome]
GO:0005776 [autophagosome]
GO:0005783 [endoplasmic reticulum]
GO:0005794 [Golgi apparatus]
GO:0005795 [Golgi stack]
GO:0005802 [trans-Golgi network]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005901 [caveola]
GO:0006520 [cellular amino acid metabolic process]
GO:0006672 [ceramide metabolic process]
GO:0006678 [glucosylceramide metabolic process]
GO:0006681 [galactosylceramide metabolic process]
GO:0006684 [sphingomyelin metabolic process]
GO:0006898 [receptor-mediated endocytosis]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0007042 [lysosomal lumen acidification]
GO:0008021 [synaptic vesicle]
GO:0008306 [associative learning]
GO:0015809 [arginine transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016236 [macroautophagy]
GO:0016242 [negative regulation of macroautophagy]
GO:0016485 [protein processing]
GO:0030163 [protein catabolic process]
GO:0030176 [integral component of endoplasmic reticulum membrane]
GO:0035235 [ionotropic glutamate receptor signaling pathway]
GO:0035752 [lysosomal lumen pH elevation]
GO:0042133 [neurotransmitter metabolic process]
GO:0042987 [amyloid precursor protein catabolic process]
GO:0043005 [neuron projection]
GO:0043066 [negative regulation of apoptotic process]
GO:0043086 [negative regulation of catalytic activity]
GO:0043524 [negative regulation of neuron apoptotic process]
GO:0045121 [membrane raft]
GO:0045861 [negative regulation of proteolysis]
GO:0047496 [vesicle transport along microtubule]
GO:0050885 [neuromuscular process controlling balance]
GO:0051082 [unfolded protein binding]
GO:0051480 [cytosolic calcium ion homeostasis]
GO:0061024 [membrane organization]
GO:0097352 [autophagosome maturation]
Show all
 438 aa
47.6 kDa 		No 9
CLN3-204
ENSP00000486178
ENST00000628023
H3BRU8 [Direct mapping]
Battenin
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   Phobius predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
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GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
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 82 aa
9.1 kDa 		No 1
CLN3-205
ENSP00000486616
ENST00000631023
H3BPM8 [Direct mapping]
Battenin
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Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   6TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
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GO:0005765 [lysosomal membrane]
GO:0007034 [vacuolar transport]
GO:0007040 [lysosome organization]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
Show all
 341 aa
36.3 kDa 		No 6

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.