Fields »
ABOUT
HELP
BLOG
NANOS1

GENERAL INFORMATION

Gene name

 NANOS1

Gene description

 Nanos homolog 1 (Drosophila)

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (skeletal muscle)
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and membranous expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
CAB012219
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Stomach

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (skeletal muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 NANOS1 (HGNC Symbol)

Synonyms

 NOS1

Description

 Nanos homolog 1 (Drosophila) (HGNC Symbol)

Entrez gene summary

 This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment. [provided by RefSeq, Sep 2015]

Chromosome

 10

Cytoband

 q26.11

Chromosome location (bp)

 119029716 - 119033732

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000188613 (version 83.38)

Entrez gene

 340719

UniProt

 Q8WY41 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8WY41

Antibodypedia

 NANOS1 antibodies

PROTEIN BROWSER
NANOS1-001
NANOS1-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NANOS1-001
ENSP00000345924
ENST00000340087
Q5T9H5 [Direct mapping]
Nanos homolog 1
Show all
Predicted intracellular proteins
Show all
GO:0003723 [RNA binding]
GO:0008270 [zinc ion binding]
Show all
 84 aa
9.2 kDa 		No 0
NANOS1-002
ENSP00000393275
ENST00000425699
Q8WY41 [Direct mapping]
Nanos homolog 1
Show all
Predicted intracellular proteins
Disease related genes
Show all
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005737 [cytoplasm]
GO:0008270 [zinc ion binding]
GO:0010631 [epithelial cell migration]
GO:0016477 [cell migration]
GO:0017148 [negative regulation of translation]
GO:0030371 [translation repressor activity]
GO:0048471 [perinuclear region of cytoplasm]
GO:1900153 [positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay]
Show all
 292 aa
30.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.