Expression of PTAR1 in cancer - Summary

GENERAL INFORMATION
Gene name	PTAR1
Gene description	Protein prenyltransferase alpha subunit repeat containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression at variable levels. Highly abundant in gastrointestinal tract.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA021248
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA021248

GENE INFORMATION
Gene name	PTAR1
Synonyms
Description	Protein prenyltransferase alpha subunit repeat containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q21.12
Chromosome location (bp)	69709522 - 69759959
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188647 (version 83.38)
Entrez gene	375743
UniProt	Q7Z6K3 (UniProt - Evidence at protein level)
neXtProt	NX_Q7Z6K3
Antibodypedia	PTAR1 antibodies

PROTEIN BROWSER

PTAR1-001	PTAR1-002	PTAR1-004	PTAR1-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PTAR1-001 ENSP00000366405 ENST00000377200	X6R9N0 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] Show all	350 aa 39.9 kDa	No	0
PTAR1-002 ENSP00000344299 ENST00000340434	Q7Z6K3 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] GO:1990234 [transferase complex] Show all	402 aa 46.4 kDa	No	0
PTAR1-004 ENSP00000440164 ENST00000472967	F5GXY1 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		29 aa 3.3 kDa	No	0
PTAR1-005 ENSP00000405943 ENST00000415701	J3KQP8 [Direct mapping] Protein prenyltransferase alpha subunit repeat-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008318 [protein prenyltransferase activity] GO:0018342 [protein prenylation] Show all	168 aa 19.3 kDa	No	0