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DUPD1

GENERAL INFORMATION

Gene name

 DUPD1

Gene description

 Dual specificity phosphatase and pro isomerase domain containing 1

Protein class

 Enzymes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Tissue enriched (skeletal muscle)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in several tissues, including skeletal myocytes.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA042964
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA042964

GENE INFORMATION

Gene name

 DUPD1 (HGNC Symbol)

Synonyms

 DUSP27

Description

 Dual specificity phosphatase and pro isomerase domain containing 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 q22.2

Chromosome location (bp)

 75037836 - 75058514

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000188716 (version 83.38)

Entrez gene

 338599

UniProt

 Q68J44 (UniProt - Evidence at protein level)

neXtProt

 NX_Q68J44

Antibodypedia

 DUPD1 antibodies

PROTEIN BROWSER
DUPD1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
DUPD1-001
ENSP00000340609
ENST00000338487
Q68J44 [Direct mapping]
Dual specificity phosphatase DUPD1
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Enzymes
   ENZYME proteins
   Hydrolases
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
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GO:0004725 [protein tyrosine phosphatase activity]
GO:0005737 [cytoplasm]
GO:0006470 [protein dephosphorylation]
GO:0008138 [protein tyrosine/serine/threonine phosphatase activity]
GO:0016311 [dephosphorylation]
GO:0016791 [phosphatase activity]
GO:0035335 [peptidyl-tyrosine dephosphorylation]
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 220 aa
25.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.