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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RBM34
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

RBM34

Gene description

RNA binding motif protein 34

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Mixed
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues. Additional nucleolar expression in squmous epithelia.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA028606
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA028606

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues showed moderate to strong cytoplasmic immunoreactivity. A majority of cases displayed additional nucleolar positivity.

GENE INFORMATION

Gene name

RBM34 (HGNC Symbol)

Synonyms

KIAA0117

Description

RNA binding motif protein 34 (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

q42.3

Chromosome location (bp)

235131183 - 235161457

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000188739 (version 83.38)

Entrez gene

23029

UniProt

P42696 (UniProt - Evidence at protein level)

neXtProt

NX_P42696

Antibodypedia

RBM34 antibodies

PROTEIN BROWSER

RBM34-001
RBM34-004
RBM34-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RBM34-001
ENSP00000386226
ENST00000408888
P42696 [Direct mapping]
RNA-binding protein 34
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0044822 [poly(A) RNA binding]
Show all
430 aa
48.6 kDa
No 0
RBM34-004
ENSP00000413409
ENST00000429912
Q5TCT4 [Direct mapping]
RNA-binding protein 34
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
Show all
211 aa
24.1 kDa
No 0
RBM34-010
ENSP00000400000
ENST00000447801
A2A2V2 [Direct mapping]
RNA-binding protein 34
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0003676 [nucleic acid binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
Show all
408 aa
45.9 kDa
No 0

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