Expression of TMEM201 in cancer - Summary - The Human Protein Atlas

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TMEM201

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM201
Gene description	Transmembrane protein 201
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear membrane expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Approved based on 1 antibody. CAB039039
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and cervical cancer (favourable).
Liver cancer p<0.001 Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

CAB039039

GENE INFORMATION
Gene name	TMEM201 (HGNC Symbol)
Synonyms	NET5, RP13-15M17.2
Description	Transmembrane protein 201 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p36.22
Chromosome location (bp)	9588922 - 9614873
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000188807 (version 83.38)
Entrez gene	199953
UniProt	Q5SNT2 (UniProt - Evidence at protein level)
neXtProt	NX_Q5SNT2
Antibodypedia	TMEM201 antibodies

PROTEIN BROWSER

TMEM201-001	TMEM201-002	TMEM201-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM201-001 ENSP00000393626 ENST00000416541	H0Y4R5 [Direct mapping] Transmembrane protein 201 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	552 aa 59.7 kDa	No	5
TMEM201-002 ENSP00000344503 ENST00000340381	Q5SNT2 [Direct mapping] Transmembrane protein 201 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 6TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005521 [lamin binding] GO:0005637 [nuclear inner membrane] GO:0007097 [nuclear migration] GO:0010761 [fibroblast migration] GO:0016021 [integral component of membrane] GO:0031965 [nuclear membrane] GO:0051015 [actin filament binding] Show all	666 aa 72.2 kDa	No	6
TMEM201-003 ENSP00000344772 ENST00000340305	Q5SNT2 [Direct mapping] Transmembrane protein 201 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005637 [nuclear inner membrane] GO:0016021 [integral component of membrane] Show all	392 aa 43.4 kDa	No	5

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.