Expression of ZDHHC11 in cancer - Summary - The Human Protein Atlas

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ZDHHC11

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZDHHC11
Gene description	Zinc finger, DHHC-type containing 11
Protein class	Enzymes Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene. Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA057886
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA057886

GENE INFORMATION
Gene name	ZDHHC11 (HGNC Symbol)
Synonyms	FLJ13153, ZNF399
Description	Zinc finger, DHHC-type containing 11 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	p15.33
Chromosome location (bp)	795606 - 850986
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000188818 (version 83.38)
Entrez gene	79844
UniProt	Q9H8X9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9H8X9
Antibodypedia	ZDHHC11 antibodies

PROTEIN BROWSER

ZDHHC11-001	ZDHHC11-002	ZDHHC11-006	ZDHHC11-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZDHHC11-001 ENSP00000283441 ENST00000283441	Q9H8X9 [Direct mapping] Probable palmitoyltransferase ZDHHC11 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	412 aa 46 kDa	No	5
ZDHHC11-002 ENSP00000427067 ENST00000511539	Q9H8X9 [Direct mapping] Probable palmitoyltransferase ZDHHC11 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005783 [endoplasmic reticulum] GO:0005794 [Golgi apparatus] GO:0006612 [protein targeting to membrane] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0018230 [peptidyl-L-cysteine S-palmitoylation] GO:0019706 [protein-cysteine S-palmitoyltransferase activity] Show all	142 aa 15.7 kDa	No	1
ZDHHC11-006 ENSP00000426873 ENST00000511193	D6RE92 [Direct mapping] Probable palmitoyltransferase ZDHHC11 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	51 aa 5.9 kDa	No	1
ZDHHC11-201 ENSP00000397719 ENST00000424784	A0A0A0MSN5 [Direct mapping] Probable palmitoyltransferase ZDHHC11 Show all	Predicted intracellular proteins Show all		213 aa 23.8 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.