We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Cytoplasmic and extracellular expression in most tissues.
ANTIBODY IHC RELIABILITY
Data reliability description
Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Breast cancers along with several cases of malignant gliomas, malignant melanomas, hepatocellular carcinomas, renal and prostate cancers exhibited moderate to strong cytoplasmic positivity. A few cases of breast cancers showed strong nuclear staining. Remaining malignant cells were in general weakly stained or negative.
GENE INFORMATION
Gene name
APOD
Synonyms
Description
Apolipoprotein D (HGNC Symbol)
Entrez gene summary
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]