Expression of SPATS2L in cancer - Summary

GENERAL INFORMATION
Gene name	SPATS2L
Gene description	Spermatogenesis associated, serine-rich 2-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	22
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA055427
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PROGNOSTIC SUMMARY
Prognostic marker in pancreatic cancer (unfavourable).
Pancreatic cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA055427

GENE INFORMATION
Gene name	SPATS2L (HGNC Symbol)
Synonyms	DNAPTP6
Description	Spermatogenesis associated, serine-rich 2-like (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q33.1
Chromosome location (bp)	200305881 - 200482263
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196141 (version 83.38)
Entrez gene	26010
UniProt	Q9NUQ6 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NUQ6
Antibodypedia	SPATS2L antibodies

PROTEIN BROWSER

SPATS2L-001	SPATS2L-002	SPATS2L-003	SPATS2L-004	SPATS2L-005	SPATS2L-008	SPATS2L-010	SPATS2L-011	SPATS2L-012	SPATS2L-013	SPATS2L-014	SPATS2L-015	SPATS2L-016	SPATS2L-017	SPATS2L-019	SPATS2L-020	SPATS2L-021	SPATS2L-022	SPATS2L-023	SPATS2L-026	SPATS2L-201	SPATS2L-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SPATS2L-001 ENSP00000351503 ENST00000358677	Q9NUQ6 [Direct mapping] SPATS2-like protein A0A024R3V0 [Target identity:100%; Query identity:100%] DNA polymerase-transactivated protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	558 aa 61.7 kDa	No	0
SPATS2L-002 ENSP00000386336 ENST00000409718	Q9NUQ6 [Direct mapping] SPATS2-like protein A0A024R3V0 [Target identity:100%; Query identity:100%] DNA polymerase-transactivated protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	558 aa 61.7 kDa	No	0
SPATS2L-003 ENSP00000386391 ENST00000409385	B8ZZZ7 [Direct mapping] DNA polymerase-transactivated protein 6, isoform CRA_b; SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] Show all	498 aa 54.9 kDa	No	0
SPATS2L-004 ENSP00000386931 ENST00000409988	Q9NUQ6 [Direct mapping] SPATS2-like protein A0A024R3V0 [Target identity:100%; Query identity:100%] DNA polymerase-transactivated protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	558 aa 61.7 kDa	No	0
SPATS2L-005 ENSP00000386730 ENST00000409140	Q9NUQ6 [Direct mapping] SPATS2-like protein A0A024R3V0 [Target identity:100%; Query identity:100%] DNA polymerase-transactivated protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	558 aa 61.7 kDa	No	0
SPATS2L-008 ENSP00000353989 ENST00000360760	Q9NUQ6 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	489 aa 54.2 kDa	No	0
SPATS2L-010 ENSP00000386310 ENST00000409151	Q9NUQ6 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	566 aa 62.7 kDa	No	0
SPATS2L-011 ENSP00000406728 ENST00000439084	C9IZC3 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	94 aa 10.7 kDa	No	0
SPATS2L-012 ENSP00000411294 ENST00000439395	C9J8M7 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	115 aa 13 kDa	No	0
SPATS2L-013 ENSP00000405506 ENST00000444012	F8WAV0 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		23 aa 2.6 kDa	No	0
SPATS2L-014 ENSP00000391467 ENST00000451764	Q9NUQ6 [Direct mapping] SPATS2-like protein A0A024R3V0 [Target identity:100%; Query identity:100%] DNA polymerase-transactivated protein 6, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	558 aa 61.7 kDa	No	0
SPATS2L-015 ENSP00000389908 ENST00000457757	F8VT91 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	188 aa 20.9 kDa	No	0
SPATS2L-016 ENSP00000396109 ENST00000423749	F2Z2S1 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	140 aa 15.7 kDa	No	0
SPATS2L-017 ENSP00000398198 ENST00000428692	Q4ZFW0 [Direct mapping] Putative uncharacterized protein DKFZP564A2416; SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		13 aa 1.5 kDa	No	0
SPATS2L-019 ENSP00000402559 ENST00000421573	C9JKE4 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	154 aa 17.2 kDa	No	0
SPATS2L-020 ENSP00000390506 ENST00000453663	C9JGM8 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	193 aa 21.6 kDa	No	0
SPATS2L-021 ENSP00000413648 ENST00000438761	C9JW67 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	238 aa 26.6 kDa	No	0
SPATS2L-022 ENSP00000413142 ENST00000449647	F8VZ02 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	173 aa 19.4 kDa	No	0
SPATS2L-023 ENSP00000386600 ENST00000409397	F8W6C2 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	266 aa 30 kDa	No	0
SPATS2L-026 ENSP00000405751 ENST00000366118	H7C2G5 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		117 aa 13.2 kDa	No	0
SPATS2L-201 ENSP00000387333 ENST00000409755	A0A0A0MSG5 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		475 aa 52.4 kDa	No	0
SPATS2L-202 ENSP00000482515 ENST00000619961	Q9NUQ6 [Direct mapping] SPATS2-like protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0043234 [protein complex] GO:0044822 [poly(A) RNA binding] Show all	588 aa 65.2 kDa	No	0