Expression of STK31 in cancer - Summary - The Human Protein Atlas

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STK31

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	STK31
Gene description	Serine/threonine kinase 31
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enriched (CACO-2)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct expression in a subset of cells in testis

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA023194
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023194

GENE INFORMATION
Gene name	STK31 (HGNC Symbol)
Synonyms	SgK396, TDRD8
Description	Serine/threonine kinase 31 (HGNC Symbol)
Entrez gene summary	This gene is similar to a mouse gene that encodes a putative protein kinase with a tudor domain, and shows testis-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	p15.3
Chromosome location (bp)	23710167 - 23832513
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196335 (version 83.38)
Entrez gene	56164
UniProt	Q9BXU1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BXU1
Antibodypedia	STK31 antibodies

PROTEIN BROWSER

STK31-001	STK31-002	STK31-006	STK31-007	STK31-008	STK31-011	STK31-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STK31-001 ENSP00000348132 ENST00000355870	Q9BXU1 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Enzymes ENZYME proteins Transferases Kinases MEMSAT3 predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001669 [acrosomal vesicle] GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	1019 aa 115.7 kDa	No	0
STK31-002 ENSP00000346660 ENST00000354639	Q9BXU1 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Enzymes ENZYME proteins Transferases Kinases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	996 aa 113.3 kDa	No	0
STK31-006 ENSP00000435974 ENST00000531170	E9PRQ0 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		43 aa 4.9 kDa	No	0
STK31-007 ENSP00000389340 ENST00000456014	C9JQW5 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		159 aa 18.2 kDa	No	0
STK31-008 ENSP00000414087 ENST00000422637	C9JPB1 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		140 aa 16.1 kDa	No	0
STK31-011 ENSP00000411852 ENST00000433467	Q9BXU1 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Enzymes ENZYME proteins Transferases Kinases Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	996 aa 113 kDa	No	0
STK31-012 ENSP00000398413 ENST00000444333	F8W6E7 [Direct mapping] Serine/threonine-protein kinase 31 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.7 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.