Expression of TSC22D2 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TSC22D2

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TSC22D2
Gene description	TSC22 domain family, member 2
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues, including testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA004926
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (unfavourable) and renal cancer (unfavourable).
Endometrial cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA004926

GENE INFORMATION
Gene name	TSC22D2 (HGNC Symbol)
Synonyms	KIAA0669, TILZ4a, TILZ4b, TILZ4c
Description	TSC22 domain family, member 2 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	q25.1
Chromosome location (bp)	150408335 - 150466431
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196428 (version 83.38)
Entrez gene	9819
UniProt	O75157 (UniProt - Evidence at protein level)
neXtProt	NX_O75157
Antibodypedia	TSC22D2 antibodies

PROTEIN BROWSER

TSC22D2-001	TSC22D2-003	TSC22D2-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TSC22D2-001 ENSP00000354543 ENST00000361875	O75157 [Direct mapping] TSC22 domain family protein 2 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Transcription factors Basic domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0006970 [response to osmotic stress] Show all	780 aa 79.2 kDa	No	0
TSC22D2-003 ENSP00000417747 ENST00000466814	H0Y865 [Direct mapping] TSC22 domain family protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	204 aa 21.7 kDa	No	0
TSC22D2-005 ENSP00000418149 ENST00000480589	H7C4U3 [Direct mapping] TSC22 domain family protein 2 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] Show all	116 aa 12.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.