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Mainly localized to the endoplasmic reticulum & vesicles. In addition localized to the nucleoplasm.
Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category
Expressed in all
Protein evidence
Evidence at protein level
Main location
Localized to the Endoplasmic reticulum (supported), Vesicles (approved)
Additional location
In addition localized to the Nucleoplasm (approved)
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
HUMAN CELLS
Summary
Mainly localized to the endoplasmic reticulum & vesicles. In addition localized to the nucleoplasm.
Caution: Based on antibodies targeting proteins from multiple genes.
Trafficking protein particle complex 2 (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is thought to be part of a large multi-subunit complex involved in the targeting and fusion of endoplasmic reticulum-to-Golgi transport vesicles with their acceptor compartment. In addition, the encoded protein can bind c-myc promoter-binding protein 1 and block its transcriptional repression capability. Mutations in this gene are a cause of spondyloepiphyseal dysplasia tarda (SEDT). A processed pseudogene of this gene is located on chromosome 19, and other pseudogenes are found on chromosomes 8 and Y. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]