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GK2

GENERAL INFORMATION

Gene name

 GK2

Gene description

 Glycerol kinase 2

Protein class

 Enzymes
Plasma proteins
Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (SCLC-21H)
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.

Reliability score

 Uncertain based on 1 antibody.
HPA060687
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA060687

GENE INFORMATION

Gene name

 GK2 (HGNC Symbol)

Synonyms

 GKP2, GKTA

Description

 Glycerol kinase 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 q21.21

Chromosome location (bp)

 79406352 - 79408293

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196475 (version 83.38)

Entrez gene

 2712

UniProt

 Q14410 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q14410

Antibodypedia

 GK2 antibodies

PROTEIN BROWSER
GK2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GK2-001
ENSP00000351706
ENST00000358842
Q14410 [Direct mapping]
Glycerol kinase 2
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Enzymes
   ENZYME proteins
   Transferases
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Plasma proteins
Protein evidence (Kim et al 2014)
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GO:0004370 [glycerol kinase activity]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005741 [mitochondrial outer membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0006071 [glycerol metabolic process]
GO:0006072 [glycerol-3-phosphate metabolic process]
GO:0006641 [triglyceride metabolic process]
GO:0016310 [phosphorylation]
GO:0016773 [phosphotransferase activity, alcohol group as acceptor]
GO:0019563 [glycerol catabolic process]
GO:0046167 [glycerol-3-phosphate biosynthetic process]
GO:0070062 [extracellular exosome]
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 553 aa
60.6 kDa 		No 2

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.