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ESRRG

GENERAL INFORMATION

Gene name

 ESRRG

Gene description

 Estrogen-related receptor gamma

Protein class

 FDA approved drug targets
Nuclear receptors
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 18
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Group enriched (RPMI-8226, SCLC-21H, SH-SY5Y)
HPA (normal tissue):Tissue enhanced (parathyroid gland)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Mainly cytoplasmic expression in few tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA044678
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA044678

GENE INFORMATION

Gene name

 ESRRG (HGNC Symbol)

Synonyms

 NR3B3

Description

 Estrogen-related receptor gamma (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011]

Chromosome

 1

Cytoband

 q41

Chromosome location (bp)

 216503246 - 217137755

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196482 (version 83.38)

Entrez gene

 2104

UniProt

 P62508 (UniProt - Evidence at protein level)

neXtProt

 NX_P62508

Antibodypedia

 ESRRG antibodies

PROTEIN BROWSER
«
ESRRG-001
ESRRG-002
ESRRG-003
ESRRG-004
ESRRG-005
ESRRG-006
ESRRG-007
ESRRG-008
ESRRG-010
ESRRG-011
ESRRG-012
ESRRG-013
ESRRG-016
ESRRG-017
ESRRG-019
ESRRG-201
ESRRG-202
ESRRG-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ESRRG-001
ENSP00000386171
ENST00000408911
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R5 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 1
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 458 aa
51.3 kDa 		No 0
ESRRG-002
ENSP00000354584
ENST00000361395
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-003
ENSP00000355907
ENST00000366940
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-004
ENSP00000352077
ENST00000359162
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-005
ENSP00000353108
ENST00000360012
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-006
ENSP00000355904
ENST00000366937
P62508 [Direct mapping]
Estrogen-related receptor gamma
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000977 [RNA polymerase II regulatory region sequence-specific DNA binding]
GO:0001228 [transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 470 aa
52.5 kDa 		No 0
ESRRG-007
ENSP00000355905
ENST00000366938
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-008
ENSP00000419514
ENST00000475275
C9JU32 [Direct mapping]
Estrogen-related receptor gamma
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0005496 [steroid binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
Show all
 354 aa
39.2 kDa 		No 0
ESRRG-010
ENSP00000419594
ENST00000493603
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-011
ENSP00000418629
ENST00000463665
P62508 [Direct mapping]
Estrogen-related receptor gamma
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 396 aa
44.1 kDa 		No 0
ESRRG-012
ENSP00000417374
ENST00000493748
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-013
ENSP00000419155
ENST00000487276
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-016
ENSP00000420370
ENST00000459955
C9JNX5 [Direct mapping]
Estrogen-related receptor gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 56 aa
5.8 kDa 		No 0
ESRRG-017
ENSP00000417900
ENST00000469486
C9J5W9 [Direct mapping]
Estrogen-related receptor gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 92 aa
9.6 kDa 		No 0
ESRRG-019
ENSP00000418895
ENST00000481543
C9J0E3 [Direct mapping]
Estrogen-related receptor gamma
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 50 aa
5.2 kDa 		No 0
ESRRG-201
ENSP00000355225
ENST00000361525
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-202
ENSP00000375761
ENST00000391890
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0
ESRRG-203
ENSP00000481528
ENST00000616180
P62508 [Direct mapping]
Estrogen-related receptor gamma
F1D8R6 [Target identity:100%; Query identity:100%]
Estrogen-related nuclear receptor gamma variant 2
Show all
Nuclear receptors
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
FDA approved drug targets
   Small molecule drugs
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003707 [steroid hormone receptor activity]
GO:0003708 [retinoic acid receptor activity]
GO:0005496 [steroid binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0008270 [zinc ion binding]
GO:0010467 [gene expression]
GO:0043401 [steroid hormone mediated signaling pathway]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0048384 [retinoic acid receptor signaling pathway]
GO:0050682 [AF-2 domain binding]
Show all
 435 aa
48.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.