Fields »
ABOUT
HELP
BLOG
PFN3

GENERAL INFORMATION

Gene name

 PFN3

Gene description

 Profilin 3

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (kidney, testis)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected
0.0500m1.01.52.02.53.03.54.04.55.05.56.06.5FPKMBreast cancer (BRCA)Cervical cancer (CESC)Colorectal cancer (COAD,READ)Endometrial cancer (UCEC)Glioma (GBM)Head and neck cancer (HNSC)Liver cancer (LIHC)Lung cancer (LUAD,LUSC)Melanoma (SKCM)Ovarian cancer (OV)Pancreatic cancer (PAAD)Prostate cancer (PRAD)Renal cancer (KICH,KIRC,KIRP)Stomach cancer (STAD)Testis cancer (TGCT)Thyroid cancer (THCA)Urothelial cancer (BLCA)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 PFN3

Synonyms

Description

 Profilin 3 (HGNC Symbol)

Entrez gene summary

 The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q35.3

Chromosome location (bp)

 177400107 - 177400636

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196570 (version 83.38)

Entrez gene

 345456

UniProt

 P60673 (UniProt - Evidence at transcript level)

neXtProt

 NX_P60673

Antibodypedia

 PFN3 antibodies

PROTEIN BROWSER
PFN3-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PFN3-001
ENSP00000351379
ENST00000358571
P60673 [Direct mapping]
Profilin-3
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003779 [actin binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005856 [cytoskeleton]
GO:0008289 [lipid binding]
GO:0030036 [actin cytoskeleton organization]
GO:0030833 [regulation of actin filament polymerization]
GO:0032233 [positive regulation of actin filament bundle assembly]
Show all
 137 aa
14.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.