Expression of POTEI in cancer - Summary - The Human Protein Atlas

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POTEI

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	POTEI
Gene description	POTE ankyrin domain family, member I
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (BEWO, K-562, U-2 OS)
HPA (normal tissue):	Group enriched (prostate, testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. Antibody staining in cells/structures not annotated, view images. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 4 antibodies. HPA041264 , HPA041271 , HPA042822 , HPA043260
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA041264	HPA041271	HPA042822	HPA043260

GENE INFORMATION
Gene name	POTEI (HGNC Symbol)
Synonyms	POTE2beta
Description	POTE ankyrin domain family, member I (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q21.1
Chromosome location (bp)	130459455 - 130509666
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196834 (version 83.38)
Entrez gene	653269
UniProt	P0CG38 (UniProt - Inferred from homology)
neXtProt	NX_P0CG38
Antibodypedia	POTEI antibodies

PROTEIN BROWSER

POTEI-001	POTEI-201	POTEI-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POTEI-001 ENSP00000392718 ENST00000451531	P0CG38 [Direct mapping] POTE ankyrin domain family member I Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001895 [retina homeostasis] GO:0003674 [molecular_function] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0070062 [extracellular exosome] Show all	1075 aa 121.3 kDa	No	0
POTEI-201 ENSP00000483193 ENST00000615053	A0A087X092 [Direct mapping] POTE ankyrin domain family member I Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	508 aa 56.9 kDa	No	0
POTEI-202 ENSP00000486532 ENST00000631234	A0A0D9SFE8 [Direct mapping] POTE ankyrin domain family member I Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	376 aa 41.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.