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FUT11

GENERAL INFORMATION

Gene name

 FUT11

Gene description

 Fucosyltransferase 11 (alpha (1,3) fucosyltransferase)

Protein class

 Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA014033
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PROGNOSTIC SUMMARY
Prognostic marker in cervical cancer (unfavourable), renal cancer (unfavourable) and breast cancer (unfavourable).
Cervical cancer p<0.001
Renal cancer p<0.001
Breast cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA014033

GENE INFORMATION

Gene name

 FUT11 (HGNC Symbol)

Synonyms

 MGC33202

Description

 Fucosyltransferase 11 (alpha (1,3) fucosyltransferase) (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 q22.2

Chromosome location (bp)

 73772291 - 73780251

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196968 (version 83.38)

Entrez gene

 170384

UniProt

 Q495W5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q495W5

Antibodypedia

 FUT11 antibodies

PROTEIN BROWSER
FUT11-001
FUT11-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FUT11-001
ENSP00000361932
ENST00000372841
Q495W5 [Direct mapping]
Alpha-(1,3)-fucosyltransferase 11
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   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000139 [Golgi membrane]
GO:0005515 [protein binding]
GO:0006486 [protein glycosylation]
GO:0008417 [fucosyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0032580 [Golgi cisterna membrane]
GO:0036065 [fucosylation]
GO:0046920 [alpha-(1->3)-fucosyltransferase activity]
GO:0070062 [extracellular exosome]
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 492 aa
55.8 kDa 		Yes 0
FUT11-201
ENSP00000378270
ENST00000394790
Q495W5 [Direct mapping]
Alpha-(1,3)-fucosyltransferase 11
Show all
   MEMSAT3 predicted membrane proteins
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000139 [Golgi membrane]
GO:0005515 [protein binding]
GO:0006486 [protein glycosylation]
GO:0008417 [fucosyltransferase activity]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0032580 [Golgi cisterna membrane]
GO:0036065 [fucosylation]
GO:0046920 [alpha-(1->3)-fucosyltransferase activity]
GO:0070062 [extracellular exosome]
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 476 aa
53.5 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.