Expression of CXorf40B in cancer - Summary - The Human Protein Atlas

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CXorf40B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CXorf40B
Gene description	Chromosome X open reading frame 40B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic and membranous expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 1 antibody. HPA060897
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PROGNOSTIC SUMMARY
Prognostic marker in thyroid cancer (unfavourable).
Thyroid cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA060897

GENE INFORMATION
Gene name	CXorf40B
Synonyms
Description	Chromosome X open reading frame 40B (HGNC Symbol)
Entrez gene summary
Chromosome	X
Cytoband	q28
Chromosome location (bp)	149929527 - 149938811
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000197021 (version 83.38)
Entrez gene	541578
UniProt	Q96DE9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96DE9
Antibodypedia	CXorf40B antibodies

PROTEIN BROWSER

CXorf40B-001	CXorf40B-002	CXorf40B-004	CXorf40B-005	CXorf40B-006	CXorf40B-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CXorf40B-001 ENSP00000359434 ENST00000370406	Q96DE9 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		158 aa 17.8 kDa	No	0
CXorf40B-002 ENSP00000347339 ENST00000355203	Q96DE9 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		158 aa 17.8 kDa	No	0
CXorf40B-004 ENSP00000474324 ENST00000370409	S4R3G8 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		147 aa 16.6 kDa	No	0
CXorf40B-005 ENSP00000474715 ENST00000483447	S4R3T8 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		45 aa 5.1 kDa	No	0
CXorf40B-006 ENSP00000359432 ENST00000370404	Q96DE9 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		158 aa 17.8 kDa	No	0
CXorf40B-007 ENSP00000417546 ENST00000462691	Q5HY62 [Direct mapping] Protein CXorf40B Show all	Predicted intracellular proteins Show all		146 aa 16.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.