Expression of ZNF420 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

ZNF420

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF420
Gene description	Zinc finger protein 420
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression with variable levels in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA053022
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in glioma (favourable) and renal cancer (favourable).
Glioma p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA053022

GENE INFORMATION
Gene name	ZNF420 (HGNC Symbol)
Synonyms	FLJ32191
Description	Zinc finger protein 420 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.12
Chromosome location (bp)	37007857 - 37130314
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197050 (version 83.38)
Entrez gene	147923
UniProt	Q8TAQ5 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TAQ5
Antibodypedia	ZNF420 antibodies

PROTEIN BROWSER

ZNF420-001	ZNF420-002	ZNF420-004	ZNF420-005	ZNF420-008	ZNF420-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF420-001 ENSP00000338770 ENST00000337995	Q8TAQ5 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	688 aa 80.2 kDa	No	0
ZNF420-002 ENSP00000306102 ENST00000304239	Q8TAQ5 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	536 aa 63 kDa	No	0
ZNF420-004 ENSP00000468736 ENST00000585862	K7ESJ1 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	89 aa 10 kDa	No	0
ZNF420-005 ENSP00000467772 ENST00000589245	K7EQC9 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	163 aa 19.4 kDa	No	0
ZNF420-008 ENSP00000466057 ENST00000587029	K7ELF6 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	88 aa 10.4 kDa	No	0
ZNF420-009 ENSP00000468387 ENST00000590332	K7ERS3 [Direct mapping] Zinc finger protein 420 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	79 aa 9.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.