Cell atlas - SLC6A17 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

SLC6A17

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Golgi apparatus
	Nucleus

Human cell
	Golgi Apparatus
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	SLC6A17
Gene description	Solute carrier family 6 (neutral amino acid transporter), member 17
Protein class	Disease related genes Potential drug targets Predicted membrane proteins Transporters
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the Golgi apparatus. In addition localized to the nucleus.
RNA cell category	Cell line enhanced (SK-MEL-30, U-87 MG, SiHa)
Protein evidence	Evidence at protein level
Main location	Localized to the Golgi apparatus (approved)
Additional location	In addition localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA007663
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SK-MEL-30, U-87 MG, SiHa) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the Golgi apparatus. In addition localized to the nucleus.

Main location

Golgi apparatus (approved)

Additional location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA007663	SK-MEL-30	Golgi apparatus
	HPA007663	SiHa	Nucleus
			Nucleoli
			Golgi apparatus

GENE INFORMATION
Gene name	SLC6A17
Synonyms
Description	Solute carrier family 6 (neutral amino acid transporter), member 17 (HGNC Symbol)
Entrez gene summary	The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	110150486 - 110202202
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197106 (version 83.38)
Entrez gene	388662
UniProt	Q9H1V8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H1V8
Antibodypedia	SLC6A17 antibodies

PROTEIN BROWSER

SLC6A17-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SLC6A17-001 ENSP00000330199 ENST00000331565	Q9H1V8 [Direct mapping] Sodium-dependent neutral amino acid transporter SLC6A17 Show all	Transporters Electrochemical Potential-driven transporters Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003333 [amino acid transmembrane transport] GO:0005328 [neurotransmitter:sodium symporter activity] GO:0005887 [integral component of plasma membrane] GO:0006836 [neurotransmitter transport] GO:0007420 [brain development] GO:0008021 [synaptic vesicle] GO:0015171 [amino acid transmembrane transporter activity] GO:0015804 [neutral amino acid transport] GO:0015816 [glycine transport] GO:0015820 [leucine transport] GO:0015824 [proline transport] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0030672 [synaptic vesicle membrane] GO:0032328 [alanine transport] Show all	727 aa 81 kDa	No	>9

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.