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ZNF655

GENERAL INFORMATION

Gene name

 ZNF655

Gene description

 Zinc finger protein 655

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 15
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and nuclear expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA029534
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PROGNOSTIC SUMMARY
Prognostic marker in breast cancer (favourable) and melanoma (unfavourable).
Breast cancer p<0.001
Melanoma p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA029534

GENE INFORMATION

Gene name

 ZNF655 (HGNC Symbol)

Synonyms

 VIK, VIK-1

Description

 Zinc finger protein 655 (HGNC Symbol)

Entrez gene summary

 This gene encodes a zinc finger protein. The zinc finger proteins are involved in DNA binding and protein-protein interactions. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 q22.1

Chromosome location (bp)

 99558406 - 99576453

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197343 (version 83.38)

Entrez gene

 79027

UniProt

 Q8N720 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N720

Antibodypedia

 ZNF655 antibodies

PROTEIN BROWSER
«
ZNF655-003
ZNF655-006
ZNF655-007
ZNF655-008
ZNF655-009
ZNF655-012
ZNF655-014
ZNF655-015
ZNF655-020
ZNF655-021
ZNF655-022
ZNF655-024
ZNF655-201
ZNF655-202
ZNF655-203
»

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF655-003
ENSP00000322363
ENST00000320583
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 181 aa
20 kDa 		No 0
ZNF655-006
ENSP00000396396
ENST00000440391
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 110 aa
12 kDa 		No 0
ZNF655-007
ENSP00000252713
ENST00000252713
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 491 aa
57.4 kDa 		No 0
ZNF655-008
ENSP00000419135
ENST00000493277
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 526 aa
61.4 kDa 		No 0
ZNF655-009
ENSP00000377718
ENST00000394163
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 491 aa
57.4 kDa 		No 0
ZNF655-012
ENSP00000392980
ENST00000425063
C9J0V9 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 103 aa
11.4 kDa 		No 0
ZNF655-014
ENSP00000403500
ENST00000454654
C9J0V9 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 103 aa
11.4 kDa 		No 0
ZNF655-015
ENSP00000398872
ENST00000452314
C9J9R2 [Direct mapping]
Zinc finger protein 655
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 99 aa
10.8 kDa 		No 0
ZNF655-020
ENSP00000389260
ENST00000422164
C9JS03 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 182 aa
21.1 kDa 		No 0
ZNF655-021
ENSP00000393750
ENST00000422647
C9JUB9 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 109 aa
12.3 kDa 		No 0
ZNF655-022
ENSP00000392244
ENST00000427931
C9IYG2 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 112 aa
12.7 kDa 		No 0
ZNF655-024
ENSP00000414969
ENST00000449244
C9JNK1 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 129 aa
13.6 kDa 		No 0
ZNF655-201
ENSP00000350530
ENST00000357864
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 110 aa
12 kDa 		No 0
ZNF655-202
ENSP00000393876
ENST00000424881
Q8N720 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
GO:2000134 [negative regulation of G1/S transition of mitotic cell cycle]
Show all
 526 aa
61.4 kDa 		No 0
ZNF655-203
ENSP00000486262
ENST00000626122
C9J0V9 [Direct mapping]
Zinc finger protein 655
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 103 aa
11.4 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.