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Malignant tissues displayed moderate cytoplasmic positivity. Strong staining was observed in occasional cases of cervical, endometrial and testicular cancers.
GENE INFORMATION
Gene name
GALP
Synonyms
Description
Galanin-like peptide (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the galanin family of neuropeptides. The encoded protein binds galanin receptors 1, 2 and 3 with the highest affinity for galanin receptor 3 and has been implicated in biological processes involving the central nervous system including hypothalamic regulation of metabolism and reproduction. A peptide encoded by a splice variant of this gene, termed alarin, has vasoactive properties, displays antimicrobial activity against E. coli, and may serve as a marker for neuroblastic tumors.[provided by RefSeq, Nov 2014]