Expression of TTC30A in cancer - Summary

GENERAL INFORMATION
Gene name	TTC30A
Gene description	Tetratricopeptide repeat domain 30A
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Expression in cilia in respiratory epithelium, fallopian tube and uterus with additional cytoplasmic expression in testis.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene. Paired antibodies with high similarity support the protein profile.
Reliability score	Supported based on 3 antibodies. HPA051714 , HPA052100 , HPA052487
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PROGNOSTIC SUMMARY
Prognostic marker in glioma (unfavourable).
Glioma p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

STAINING SUMMARY

HPA051714	HPA052100	HPA052487

GENE INFORMATION
Gene name	TTC30A (HGNC Symbol)
Synonyms	FLJ13946, IFT70A
Description	Tetratricopeptide repeat domain 30A (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	q31.2
Chromosome location (bp)	177612992 - 177618966
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197557 (version 83.38)
Entrez gene	92104
UniProt	Q86WT1 (UniProt - Evidence at transcript level)
neXtProt	NX_Q86WT1
Antibodypedia	TTC30A antibodies

PROTEIN BROWSER

TTC30A-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TTC30A-001 ENSP00000347915 ENST00000355689	Q86WT1 [Direct mapping] Tetratricopeptide repeat protein 30A Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042073 [intraciliary transport] GO:0042384 [cilium assembly] Show all	665 aa 76.1 kDa	No	0