Expression of CR1L in cancer - Summary - The Human Protein Atlas

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CR1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CR1L
Gene description	Complement component (3b/4b) receptor 1-like
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (testis cancer)
HPA (cell line):	Group enriched (HEL, HMC-1, K-562)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in lymphoid tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA049348
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (testis cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA049348

GENE INFORMATION
Gene name	CR1L
Synonyms
Description	Complement component (3b/4b) receptor 1-like (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q32.2
Chromosome location (bp)	207645113 - 207738416
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197721 (version 83.38)
Entrez gene	1379
UniProt	Q2VPA4 (UniProt - Evidence at protein level)
neXtProt	NX_Q2VPA4
Antibodypedia	CR1L antibodies

PROTEIN BROWSER

CR1L-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CR1L-003 ENSP00000421736 ENST00000508064	Q2VPA4 [Direct mapping] Complement component receptor 1-like protein Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005576 [extracellular region] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0043235 [receptor complex] Show all	569 aa 62.7 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.