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RPL37A

GENERAL INFORMATION

Gene name

 RPL37A

Gene description

 Ribosomal protein L37a

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA065327
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA065327

GENE INFORMATION

Gene name

 RPL37A (HGNC Symbol)

Synonyms

 L37A

Description

 Ribosomal protein L37a (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L37AE family of ribosomal proteins. It is located in the cytoplasm. The protein contains a C4-type zinc finger-like domain. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

 2

Cytoband

 q35

Chromosome location (bp)

 216498189 - 216579180

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197756 (version 83.38)

Entrez gene

 6168

UniProt

 P61513 (UniProt - Evidence at protein level)

neXtProt

 NX_P61513

Antibodypedia

 RPL37A antibodies

PROTEIN BROWSER
RPL37A-001
RPL37A-007
RPL37A-008
RPL37A-009
RPL37A-010
RPL37A-011
RPL37A-013

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL37A-001
ENSP00000418082
ENST00000491306
P61513 [Direct mapping]
60S ribosomal protein L37a
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Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003735 [structural constituent of ribosome]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0005925 [focal adhesion]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0046872 [metal ion binding]
GO:0070062 [extracellular exosome]
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 92 aa
10.3 kDa 		No 0
RPL37A-007
ENSP00000410240
ENST00000456586
C9J4Z3 [Direct mapping]
60S ribosomal protein L37a; Ribosomal protein L37a, isoform CRA_c
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 68 aa
7.6 kDa 		No 0
RPL37A-008
ENSP00000388690
ENST00000446558
E9PEL3 [Direct mapping]
60S ribosomal protein L37a
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 75 aa
8.5 kDa 		No 0
RPL37A-009
ENSP00000469607
ENST00000598925
M0R0A1 [Direct mapping]
60S ribosomal protein L37a
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   TMHMM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 60 aa
6.8 kDa 		No 0
RPL37A-010
ENSP00000472653
ENST00000427280
M0R2L6 [Direct mapping]
60S ribosomal protein L37a
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 88 aa
10 kDa 		No 0
RPL37A-011
ENSP00000470348
ENST00000600880
Q6P4E4 [Direct mapping]
60S ribosomal protein L37a; RPL37A protein; cDNA FLJ76565, highly similar to Homo sapiens ribosomal protein L37a, mRNA
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 72 aa
8.1 kDa 		No 0
RPL37A-013
ENSP00000471102
ENST00000441179
M0R0A1 [Direct mapping]
60S ribosomal protein L37a
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   TMHMM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005840 [ribosome]
GO:0006412 [translation]
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 60 aa
6.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.