Expression of FAM118B in cancer - Summary - The Human Protein Atlas

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FAM118B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM118B
Gene description	Family with sequence similarity 118, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in most cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA041644 , HPA042100
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041644	HPA042100

GENE INFORMATION
Gene name	FAM118B (HGNC Symbol)
Synonyms	FLJ21103
Description	Family with sequence similarity 118, member B (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q24.2
Chromosome location (bp)	126211414 - 126262986
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197798 (version 83.38)
Entrez gene	79607
UniProt	Q9BPY3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BPY3
Antibodypedia	FAM118B antibodies

PROTEIN BROWSER

FAM118B-001	FAM118B-003	FAM118B-004	FAM118B-005	FAM118B-008	FAM118B-009	FAM118B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM118B-001 ENSP00000433343 ENST00000533050	Q9BPY3 [Direct mapping] Protein FAM118B A0A024R3L8 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0015030 [Cajal body] Show all	351 aa 39.5 kDa	No	0
FAM118B-003 ENSP00000432712 ENST00000529731	G3V179 [Direct mapping] Protein FAM118B; Uncharacterized protein Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		275 aa 30.8 kDa	No	0
FAM118B-004 ENSP00000353321 ENST00000360194	J3KP39 [Direct mapping] Protein FAM118B Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		350 aa 39.4 kDa	No	0
FAM118B-005 ENSP00000437285 ENST00000530043	E9PMW3 [Direct mapping] Protein FAM118B Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		153 aa 17.1 kDa	No	0
FAM118B-008 ENSP00000434952 ENST00000528985	E9PMJ2 [Direct mapping] Protein FAM118B Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		347 aa 39.1 kDa	No	0
FAM118B-009 ENSP00000435754 ENST00000525338	E9PIM5 [Direct mapping] Protein FAM118B Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		235 aa 26.5 kDa	No	0
FAM118B-201 ENSP00000487554 ENST00000627851	G3V179 [Direct mapping] Protein FAM118B; Uncharacterized protein Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		275 aa 30.8 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.