Expression of FAM212B in cancer - Summary - The Human Protein Atlas

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FAM212B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM212B
Gene description	Family with sequence similarity 212, member B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (glioma)
HPA (cell line):	Cell line enhanced (U-87 MG)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA027809 , HPA027811
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PROGNOSTIC SUMMARY
Prognostic marker in head and neck cancer (favourable).
Head and neck cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027809	HPA027811

GENE INFORMATION
Gene name	FAM212B (HGNC Symbol)
Synonyms	C1orf183, FLJ31105
Description	Family with sequence similarity 212, member B (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p13.2
Chromosome location (bp)	111680630 - 111755824
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000197852 (version 83.38)
Entrez gene	55924
UniProt	Q9NTI7 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NTI7
Antibodypedia	FAM212B antibodies

PROTEIN BROWSER

FAM212B-001	FAM212B-002	FAM212B-003	FAM212B-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM212B-001 ENSP00000349805 ENST00000357260	Q9NTI7 [Direct mapping] Protein FAM212B Show all	Predicted intracellular proteins Show all		297 aa 32.8 kDa	No	0
FAM212B-002 ENSP00000408238 ENST00000444059	Q9NTI7 [Direct mapping] Protein FAM212B Show all	Predicted intracellular proteins Show all		282 aa 30.9 kDa	No	0
FAM212B-003 ENSP00000436075 ENST00000534365	E9PR53 [Direct mapping] Protein FAM212B Show all	Predicted intracellular proteins Show all		114 aa 12.5 kDa	No	0
FAM212B-006 ENSP00000437205 ENST00000527621	E9PND8 [Direct mapping] Protein FAM212B Show all	Predicted intracellular proteins Show all		182 aa 20 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.