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KIF13B

GENERAL INFORMATION

Gene name

 KIF13B

Gene description

 Kinesin family member 13B

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Tissue enriched (parathyroid gland)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic and membranous staining in parathyroid gland.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending retesting.

Reliability score

 Approved based on 1 antibody.
HPA025023
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable), pancreatic cancer (unfavourable), head and neck cancer (favourable) and colorectal cancer (favourable).
Renal cancer p<0.001
Pancreatic cancer p<0.001
Head and neck cancer p<0.001
Colorectal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA025023

GENE INFORMATION

Gene name

 KIF13B (HGNC Symbol)

Synonyms

 GAKIN, KIAA0639

Description

 Kinesin family member 13B (HGNC Symbol)

Entrez gene summary

Chromosome

 8

Cytoband

 p12

Chromosome location (bp)

 29067279 - 29263124

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197892 (version 83.38)

Entrez gene

 23303

UniProt

 Q9NQT8 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NQT8

Antibodypedia

 KIF13B antibodies

PROTEIN BROWSER
KIF13B-001
KIF13B-004
KIF13B-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KIF13B-001
ENSP00000427900
ENST00000524189
Q9NQT8 [Direct mapping]
Kinesin-like protein KIF13B
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0005902 [microvillus]
GO:0006605 [protein targeting]
GO:0007018 [microtubule-based movement]
GO:0007165 [signal transduction]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
GO:0019901 [protein kinase binding]
GO:0030424 [axon]
GO:0033270 [paranode region of axon]
GO:0042110 [T cell activation]
GO:0050770 [regulation of axonogenesis]
GO:0071889 [14-3-3 protein binding]
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 1826 aa
202.8 kDa 		No 0
KIF13B-004
ENSP00000429201
ENST00000521515
E7ERX9 [Direct mapping]
Kinesin-like protein
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003777 [microtubule motor activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005871 [kinesin complex]
GO:0005874 [microtubule]
GO:0007018 [microtubule-based movement]
GO:0008017 [microtubule binding]
GO:0008152 [metabolic process]
GO:0016887 [ATPase activity]
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 743 aa
83.9 kDa 		No 0
KIF13B-006
ENSP00000429106
ENST00000523130
H0YBA8 [Direct mapping]
Kinesin-like protein KIF13B
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0003777 [microtubule motor activity]
GO:0005871 [kinesin complex]
GO:0007018 [microtubule-based movement]
GO:0016887 [ATPase activity]
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 418 aa
43.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.