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Moderate to strong cytoplasmic positivity was seen in most cancer cells. Gliomas, lymphomas, prostate and testicular cancers were mainly negative or showed weak staining.
Cancer cells generally showed moderate to strong cytoplasmic immunoreactivity. Prostate cancers, gliomas and lymphomas, several cases of basal cell carcinomas, testicular and breast cancers were weakly stained or negative.
Most of the cancer cells displayed weak to moderate cytoplasmic positivity with additional membranous staining in a few cases. A few cases of pancreatic cancers were strongly stained. Gliomas and most cases of lymphomas were negative.
Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0000302 [response to reactive oxygen species] GO:0003756 [protein disulfide isomerase activity] GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005788 [endoplasmic reticulum lumen] GO:0005789 [endoplasmic reticulum membrane] GO:0006457 [protein folding] GO:0006464 [cellular protein modification process] GO:0009266 [response to temperature stimulus] GO:0010260 [organ senescence] GO:0015035 [protein disulfide oxidoreductase activity] GO:0016020 [membrane] GO:0016491 [oxidoreductase activity] GO:0016671 [oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor] GO:0019471 [4-hydroxyproline metabolic process] GO:0022417 [protein maturation by protein folding] GO:0030198 [extracellular matrix organization] GO:0030425 [dendrite] GO:0030968 [endoplasmic reticulum unfolded protein response] GO:0034976 [response to endoplasmic reticulum stress] GO:0043231 [intracellular membrane-bounded organelle] GO:0044267 [cellular protein metabolic process] GO:0045454 [cell redox homeostasis] GO:0050873 [brown fat cell differentiation] GO:0051085 [chaperone mediated protein folding requiring cofactor] GO:0051209 [release of sequestered calcium ion into cytosol] GO:0055114 [oxidation-reduction process] GO:0070059 [intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress] GO:0071456 [cellular response to hypoxia]