Expression of MAK16 in cancer - Summary - The Human Protein Atlas

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MAK16

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MAK16
Gene description	MAK16 homolog
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nucleolar and cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA044417 , HPA050574
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable) and renal cancer (unfavourable).
Liver cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA044417	HPA050574

GENE INFORMATION
Gene name	MAK16 (HGNC Symbol)
Synonyms	MAK16L, RBM13
Description	MAK16 homolog (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	p12
Chromosome location (bp)	33484750 - 33501260
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198042 (version 83.38)
Entrez gene	84549
UniProt	Q9BXY0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXY0
Antibodypedia	MAK16 antibodies

PROTEIN BROWSER

MAK16-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MAK16-001 ENSP00000353246 ENST00000360128	Q9BXY0 [Direct mapping] Protein MAK16 homolog Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005730 [nucleolus] GO:0043231 [intracellular membrane-bounded organelle] GO:0044822 [poly(A) RNA binding] Show all	300 aa 35.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.