Expression of POTEH in cancer - Summary - The Human Protein Atlas

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POTEH

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	POTEH
Gene description	POTE ankyrin domain family, member H
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (prostate cancer)
HPA (cell line):	Cell line enhanced (U-2 OS)
HPA (normal tissue):	Group enriched (prostate, testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

RNA-based expert annotation gave inconclusive results.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining not consistent with RNA expression data. Caution, targets protein from more than one gene. Antibody staining in cells/structures not annotated, view images.
Reliability score	Uncertain based on 1 antibody. HPA042822
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (prostate cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042822

GENE INFORMATION
Gene name	POTEH (HGNC Symbol)
Synonyms	A26C3, ACTBL1, CT104.7, POTE22
Description	POTE ankyrin domain family, member H (HGNC Symbol)
Entrez gene summary
Chromosome	22
Cytoband	q11.1
Chromosome location (bp)	15690026 - 15721631
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000198062 (version 83.38)
Entrez gene	23784
UniProt	Q6S545 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6S545
Antibodypedia	POTEH antibodies

PROTEIN BROWSER

POTEH-001	POTEH-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
POTEH-001 ENSP00000340610 ENST00000343518	Q6S545 [Direct mapping] POTE ankyrin domain family member H Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	545 aa 61 kDa	No	0
POTEH-201 ENSP00000477748 ENST00000621704	A0A087WTB9 [Direct mapping] POTE ankyrin domain family member H Show all	Phobius predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	508 aa 57 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.