Expression of RP11-566K11.2 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RP11-566K11.2

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RP11-566K11.2
Gene description
Protein class	Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enriched (SK-MEL-30)
HPA (normal tissue):	Tissue enhanced (skin)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene. External characterization data supports antibody staining. Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 3 antibodies. HPA043640 , HPA046280 , CAB011512
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043640	HPA046280	CAB011512

Cancer	Cancer staining
Breast cancer
Carcinoid
Cervical cancer
Colorectal cancer
Endometrial cancer
Glioma
Head and neck cancer
Liver cancer
Lung cancer
Lymphoma

Cancer	Cancer staining
Melanoma
Ovarian cancer
Pancreatic cancer
Prostate cancer
Renal cancer
Skin cancer
Stomach cancer
Testis cancer
Thyroid cancer
Urothelial cancer

Staining summary	A few gliomas, carcinoids, cholangiocarcinomas, thyroid, testicular, prostate, ovarian and pancreatic cancers showed weak to moderate staining. Other cancer cells were negative.

GENE INFORMATION
Gene name	RP11-566K11.2
Synonyms
Description
Entrez gene summary
Chromosome	16
Cytoband	q24.3
Chromosome location (bp)	89919165 - 89936092
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198211 (version 83.38)
Entrez gene
UniProt
neXtProt
Antibodypedia	RP11-566K11.2 antibodies

PROTEIN BROWSER

RP11-566K11.2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RP11-566K11.2-001 ENSP00000451560 ENST00000556922	A0A0B4J269 [Direct mapping] Tubulin beta-3 chain Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0003924 [GTPase activity] GO:0004930 [G-protein coupled receptor activity] GO:0005200 [structural constituent of cytoskeleton] GO:0005525 [GTP binding] GO:0005874 [microtubule] GO:0007017 [microtubule-based process] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0043234 [protein complex] GO:0051258 [protein polymerization] Show all	797 aa 88.4 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.