Tissue expression of MT-ND6 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	MT-ND6
Gene description	Mitochondrially encoded NADH dehydrogenase 6
Protein class	Disease related genes Enzymes Potential drug targets Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	MT-ND6 (HGNC Symbol)
Synonyms	MTND6, NAD6, ND6
Description	Mitochondrially encoded NADH dehydrogenase 6 (HGNC Symbol)
Entrez gene summary
Chromosome	MT
Cytoband
Chromosome location (bp)	14149 - 14673
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198695 (version 83.38)
Entrez gene	4541
UniProt	P03923 (UniProt - Evidence at protein level)
neXtProt	NX_P03923
Antibodypedia	MT-ND6 antibodies

PROTEIN BROWSER

MT-ND6-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MT-ND6-201 ENSP00000354665 ENST00000361681	P03923 [Direct mapping] NADH-ubiquinone oxidoreductase chain 6 U5Z977 [Target identity:100%; Query identity:100%] NADH-ubiquinone oxidoreductase chain 6 Show all	Enzymes ENZYME proteins Oxidoreductases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Disease related genes Potential drug targets Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0008137 [NADH dehydrogenase (ubiquinone) activity] GO:0016021 [integral component of membrane] GO:0022904 [respiratory electron transport chain] GO:0035094 [response to nicotine] GO:0042220 [response to cocaine] GO:0042542 [response to hydrogen peroxide] GO:0044237 [cellular metabolic process] GO:0044281 [small molecule metabolic process] GO:0055114 [oxidation-reduction process] GO:0070469 [respiratory chain] Show all	174 aa 18.6 kDa	Yes	5