Expression of APCDD1L in cancer - Summary - The Human Protein Atlas

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APCDD1L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	APCDD1L
Gene description	Adenomatosis polyposis coli down-regulated 1-like
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Group enriched (BJ, HUVEC TERT2, TIME, U-138 MG, U-251 MG, U-87 MG)
HPA (normal tissue):	Tissue enhanced (breast, salivary gland)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA067015
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA067015

GENE INFORMATION
Gene name	APCDD1L (HGNC Symbol)
Synonyms	FLJ90166
Description	Adenomatosis polyposis coli down-regulated 1-like (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q13.32
Chromosome location (bp)	58459101 - 58515131
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198768 (version 83.38)
Entrez gene	164284
UniProt	Q8NCL9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NCL9
Antibodypedia	APCDD1L antibodies

PROTEIN BROWSER

APCDD1L-001	APCDD1L-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APCDD1L-001 ENSP00000360191 ENST00000371149	Q8NCL9 [Direct mapping] Protein APCDD1-like Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	501 aa 55.6 kDa	Yes	1
APCDD1L-003 ENSP00000396856 ENST00000425773	A2A2P3 [Direct mapping] Protein APCDD1-like Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		80 aa 8.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.