Expression of ZNF277 in cancer - Summary - The Human Protein Atlas

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ZNF277

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF277
Gene description	Zinc finger protein 277
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA027307
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA027307

GENE INFORMATION
Gene name	ZNF277 (HGNC Symbol)
Synonyms	NRIF4, ZNF277P
Description	Zinc finger protein 277 (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q31.1
Chromosome location (bp)	112206588 - 112343096
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198839 (version 83.38)
Entrez gene	11179
UniProt	Q9NRM2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9NRM2
Antibodypedia	ZNF277 antibodies

PROTEIN BROWSER

ZNF277-001	ZNF277-003	ZNF277-004	ZNF277-007	ZNF277-008

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF277-001 ENSP00000354501 ENST00000361822	Q9NRM2 [Direct mapping] Zinc finger protein 277 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000979 [RNA polymerase II core promoter sequence-specific DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] GO:0070301 [cellular response to hydrogen peroxide] GO:2000772 [regulation of cellular senescence] Show all	450 aa 52.8 kDa	No	0
ZNF277-003 ENSP00000402292 ENST00000450657	G5E9M4 [Direct mapping] Zinc finger protein 277; Zinc finger protein 277, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	290 aa 33.9 kDa	No	0
ZNF277-004 ENSP00000410538 ENST00000421043	C9J3B6 [Direct mapping] Zinc finger protein 277 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		98 aa 10.5 kDa	No	0
ZNF277-007 ENSP00000390359 ENST00000425229	C9JH62 [Direct mapping] Zinc finger protein 277 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0046872 [metal ion binding] Show all	199 aa 22.7 kDa	No	0
ZNF277-008 ENSP00000415735 ENST00000421864	H7C460 [Direct mapping] Zinc finger protein 277 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		118 aa 13.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.