Expression of RUNDC1 in cancer - Summary - The Human Protein Atlas

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RUNDC1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RUNDC1
Gene description	RUN domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA023726
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023726

GENE INFORMATION
Gene name	RUNDC1 (HGNC Symbol)
Synonyms	DKFZp761H0421
Description	RUN domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.31
Chromosome location (bp)	42980565 - 42993690
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198863 (version 83.38)
Entrez gene	146923
UniProt	Q96C34 (UniProt - Evidence at protein level)
neXtProt	NX_Q96C34
Antibodypedia	RUNDC1 antibodies

PROTEIN BROWSER

RUNDC1-001	RUNDC1-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RUNDC1-001 ENSP00000354622 ENST00000361677	Q96C34 [Direct mapping] RUN domain-containing protein 1 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		613 aa 67.6 kDa	No	0
RUNDC1-004 ENSP00000467953 ENST00000589705	K7EQS2 [Direct mapping] RUN domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		263 aa 29.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.