Expression of STKLD1 in cancer - Summary - The Human Protein Atlas

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STKLD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	STKLD1
Gene description	Serine/threonine kinase-like domain containing 1
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA029902
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA029902

GENE INFORMATION
Gene name	STKLD1 (HGNC Symbol)
Synonyms	C9orf96, MGC43306, SGK071
Description	Serine/threonine kinase-like domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q34.2
Chromosome location (bp)	133376367 - 133406096
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000198870 (version 83.38)
Entrez gene	169436
UniProt	Q8NE28 (UniProt - Evidence at transcript level)
neXtProt	NX_Q8NE28
Antibodypedia	STKLD1 antibodies

PROTEIN BROWSER

STKLD1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STKLD1-001 ENSP00000361025 ENST00000371957	Q8NE28 [Direct mapping] Serine/threonine kinase-like domain-containing protein STKLD1 Show all	Enzymes Kinases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005488 [binding] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	680 aa 75.7 kDa	No	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.