Fields »
ABOUT
HELP
BLOG
MAGEE1

GENERAL INFORMATION

Gene name

 MAGEE1

Gene description

 Melanoma antigen family E1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Mixed
FANTOM5:Group enriched (brain, caudate, cerebellum, hippocampus, pituitary gland)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several tissues, most abundant in CNS.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA003047
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus, pituitary gland)

GENE INFORMATION

Gene name

 MAGEE1 (HGNC Symbol)

Synonyms

 DAMAGE, KIAA1587

Description

 Melanoma antigen family E1 (HGNC Symbol)

Entrez gene summary

 This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010]

Chromosome

 X

Cytoband

 q13.3

Chromosome location (bp)

 76427724 - 76431353

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000198934 (version 83.38)

Entrez gene

 57692

UniProt

 Q9HCI5 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HCI5

Antibodypedia

 MAGEE1 antibodies

PROTEIN BROWSER
MAGEE1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAGEE1-001
ENSP00000354912
ENST00000361470
Q9HCI5 [Direct mapping]
Melanoma-associated antigen E1
Show all
   MEMSAT3 predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005886 [plasma membrane]
GO:0008150 [biological_process]
GO:0016010 [dystrophin-associated glycoprotein complex]
GO:0030425 [dendrite]
GO:0045211 [postsynaptic membrane]
GO:0048471 [perinuclear region of cytoplasm]
Show all
 957 aa
103.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.