Expression of ZNF525 in cancer - Summary - The Human Protein Atlas

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ZNF525

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF525
Gene description	Zinc finger protein 525
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA047105
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047105

GENE INFORMATION
Gene name	ZNF525 (HGNC Symbol)
Synonyms	KIAA1979
Description	Zinc finger protein 525 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.42
Chromosome location (bp)	53330675 - 53392217
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000203326 (version 83.38)
Entrez gene
UniProt
neXtProt
Antibodypedia	ZNF525 antibodies

PROTEIN BROWSER

ZNF525-001	ZNF525-002	ZNF525-003	ZNF525-005	ZNF525-008	ZNF525-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF525-001 ENSP00000419136 ENST00000467003	J3KR62 [Direct mapping] Zinc finger protein 525 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	443 aa 51.8 kDa	No	0
ZNF525-002 ENSP00000417696 ENST00000474037	J3KR51 [Direct mapping] HCG1787564; Zinc finger protein 525 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	479 aa 56 kDa	No	0
ZNF525-003 ENSP00000418468 ENST00000475179	E7ENB8 [Direct mapping] Zinc finger protein 525 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	50 aa 5.9 kDa	No	0
ZNF525-005 ENSP00000420476 ENST00000491101	E7EUL5 [Direct mapping] Zinc finger protein 525 Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	119 aa 13.7 kDa	No	0
ZNF525-008 ENSP00000470407 ENST00000593918	M0QZA4 [Direct mapping] Zinc finger protein 525 Show all	Predicted intracellular proteins Show all	GO:0003676 [nucleic acid binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0006355 [regulation of transcription, DNA-templated] Show all	52 aa 6.1 kDa	No	0
ZNF525-201 ENSP00000489237 ENST00000635711	A0A096LPF2 [Target identity:100%; Query identity:100%] Zinc finger protein 525 Show all	Predicted intracellular proteins Show all	GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006355 [regulation of transcription, DNA-templated] GO:0006412 [translation] Show all	51 aa 6.3 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.