Expression of GPR52 in cancer - Summary - The Human Protein Atlas

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GPR52

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPR52
Gene description	G protein-coupled receptor 52
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA028575
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA028575

GENE INFORMATION
Gene name	GPR52
Synonyms
Description	G protein-coupled receptor 52 (HGNC Symbol)
Entrez gene summary	Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM, Jul 2002]
Chromosome	1
Cytoband	q25.1
Chromosome location (bp)	174448111 - 174449198
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000203737 (version 83.38)
Entrez gene	9293
UniProt	Q9Y2T5 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y2T5
Antibodypedia	GPR52 antibodies

PROTEIN BROWSER

GPR52-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR52-001 ENSP00000356658 ENST00000367685	Q9Y2T5 [Direct mapping] Probable G-protein coupled receptor 52 F2YGU0 [Target identity:100%; Query identity:100%] G protein-coupled receptor 52 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005887 [integral component of plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007606 [sensory perception of chemical stimulus] GO:0008227 [G-protein coupled amine receptor activity] GO:0010579 [positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	361 aa 41.4 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.