Expression of LELP1 in cancer - Summary - The Human Protein Atlas

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LELP1

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LELP1
Gene description	Late cornified envelope-like proline-rich 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (testis cancer)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Specific cytoplasmic and nuclear expression in spermatozoa.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 1 antibody. HPA070231
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (testis cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA070231

GENE INFORMATION
Gene name	LELP1
Synonyms
Description	Late cornified envelope-like proline-rich 1 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.3
Chromosome location (bp)	153203443 - 153205120
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203784 (version 83.38)
Entrez gene	149018
UniProt	Q5T871 (UniProt - Inferred from homology)
neXtProt	NX_Q5T871
Antibodypedia	LELP1 antibodies

PROTEIN BROWSER

LELP1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LELP1-001 ENSP00000357736 ENST00000368747	Q5T871 [Direct mapping] Late cornified envelope-like proline-rich protein 1 Show all	Predicted intracellular proteins Show all	GO:0001533 [cornified envelope] GO:0005198 [structural molecule activity] GO:0005737 [cytoplasm] GO:0018149 [peptide cross-linking] GO:0030216 [keratinocyte differentiation] Show all	98 aa 10.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.