Expression of HIST2H3PS2 in cancer - Summary - The Human Protein Atlas

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HIST2H3PS2

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	HIST2H3PS2
Gene description	Histone cluster 2, H3, pseudogene 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Cell line enhanced (BJ, NB-4, SH-SY5Y, THP-1, U-2197, U-87 MG)
HPA (normal tissue):	Tissue enhanced (adrenal gland, spleen)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Caution, targets protein from more than one gene. Correlation with RNA expression data cannot be evaluated due to technical limitations (poly-A tail missing).
Reliability score	Supported based on 1 antibody. HPA042570
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042570

GENE INFORMATION
Gene name	HIST2H3PS2 (HGNC Symbol)
Synonyms	p06
Description	Histone cluster 2, H3, pseudogene 2 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	q21.1
Chromosome location (bp)	143905556 - 143905966
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203818 (version 83.38)
Entrez gene
UniProt
neXtProt
Antibodypedia	HIST2H3PS2 antibodies

PROTEIN BROWSER

HIST2H3PS2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
HIST2H3PS2-001 ENSP00000476960 ENST00000392948	Q5TEC6 [Direct mapping] Histone H3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000786 [nucleosome] GO:0003677 [DNA binding] GO:0005634 [nucleus] GO:0046982 [protein heterodimerization activity] Show all	136 aa 15.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.