Expression of EFCAB7 in cancer - Summary

GENERAL INFORMATION
Gene name	EFCAB7
Gene description	EF-hand calcium binding domain 7
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in cells in seminiferous ducts and distinct expression in cilia in several cell types.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Protein expression in respiratory epithelia can be correlated with lung RNA expression data.
Reliability score	Supported based on 3 antibodies. HPA029611 , HPA029612 , HPA029613
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PROGNOSTIC SUMMARY
Prognostic marker in glioma (favourable).
Glioma p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

STAINING SUMMARY

HPA029611	HPA029612	HPA029613

GENE INFORMATION
Gene name	EFCAB7 (HGNC Symbol)
Synonyms	KIAA1799, RP4-534K7.1
Description	EF-hand calcium binding domain 7 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p31.3
Chromosome location (bp)	63523372 - 63572693
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203965 (version 83.38)
Entrez gene	84455
UniProt	A8K855 (UniProt - Evidence at transcript level)
neXtProt	NX_A8K855
Antibodypedia	EFCAB7 antibodies

PROTEIN BROWSER

EFCAB7-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EFCAB7-001 ENSP00000360129 ENST00000371088	A8K855 [Direct mapping] EF-hand calcium-binding domain-containing protein 7 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0072372 [primary cilium] Show all	629 aa 72 kDa	No	0