Expression of LDLRAD1 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

LDLRAD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	LDLRAD1
Gene description	Low density lipoprotein receptor class A domain containing 1
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (endometrial cancer)
HPA (cell line):	Cell line enhanced (CAPAN-2, Hep G2)
HPA (normal tissue):	Tissue enriched (fallopian tube)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective expression in cilia in fallopian tube.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA052489
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (endometrial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA052489

GENE INFORMATION
Gene name	LDLRAD1
Synonyms
Description	Low density lipoprotein receptor class A domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband	p32.3
Chromosome location (bp)	54007299 - 54018186
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000203985 (version 83.38)
Entrez gene	388633
UniProt	Q5T700 (UniProt - Evidence at protein level)
neXtProt	NX_Q5T700
Antibodypedia	LDLRAD1 antibodies

PROTEIN BROWSER

LDLRAD1-001	LDLRAD1-002	LDLRAD1-201	LDLRAD1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LDLRAD1-001 ENSP00000360411 ENST00000371360	Q5T700 [Direct mapping] Low-density lipoprotein receptor class A domain-containing protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	205 aa 21.8 kDa	No	1
LDLRAD1-002 ENSP00000360413 ENST00000371362	Q5T700 [Direct mapping] Low-density lipoprotein receptor class A domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	116 aa 12.7 kDa	No	0
LDLRAD1-201 ENSP00000411017 ENST00000420619	Q5T700 [Direct mapping] Low-density lipoprotein receptor class A domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	166 aa 18.2 kDa	No	0
LDLRAD1-202 ENSP00000445871 ENST00000545928	Q5T700 [Direct mapping] Low-density lipoprotein receptor class A domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] Show all	162 aa 17.7 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.