Expression of GLT6D1 in cancer - Summary - The Human Protein Atlas

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GLT6D1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GLT6D1
Gene description	Glycosyltransferase 6 domain containing 1
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA023424
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA023424

GENE INFORMATION
Gene name	GLT6D1 (HGNC Symbol)
Synonyms	GLTDC1
Description	Glycosyltransferase 6 domain containing 1 (HGNC Symbol)
Entrez gene summary	The GT6 glycosyltransferases gene family, which includes the ABO blood group (ABO; MIM 110300) and GLT6D1, shows a complex evolution pattern, with multiple events of gain and loss in different mammal species. In humans, the ABO gene is considered the sole functional member, although the O allele is null and is fixed in certain populations (summary by Casals et al. (2009) [PubMed 19218399]).[supplied by OMIM, Jan 2011]
Chromosome	9
Cytoband	q34.3
Chromosome location (bp)	135623656 - 135639540
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000204007 (version 83.38)
Entrez gene	360203
UniProt	Q7Z4J2 (UniProt - Evidence at transcript level)
neXtProt	NX_Q7Z4J2
Antibodypedia	GLT6D1 antibodies

PROTEIN BROWSER

GLT6D1-001	GLT6D1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GLT6D1-001 ENSP00000360829 ENST00000371763	Q7Z4J2 [Direct mapping] Glycosyltransferase 6 domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005975 [carbohydrate metabolic process] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016758 [transferase activity, transferring hexosyl groups] Show all	276 aa 32.6 kDa	Yes	0
GLT6D1-201 ENSP00000483037 ENST00000613244	A0A087X017 [Direct mapping] Glycosyltransferase 6 domain-containing protein 1 Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005975 [carbohydrate metabolic process] GO:0016020 [membrane] GO:0016758 [transferase activity, transferring hexosyl groups] Show all	307 aa 36.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.