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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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IFIT1B
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PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

IFIT1B

Gene description

Interferon-induced protein with tetratricopeptide repeats 1B

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Not detected
HPA (cell line):Not detected
HPA (normal tissue):Group enriched (bone marrow, placenta)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective cytoplasmic expression in a subset of lymphoid cells.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA062924
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PROGNOSTIC SUMMARY

Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA062924

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

Cancer tissues were negative.

GENE INFORMATION

Gene name

IFIT1B (HGNC Symbol)

Synonyms

bA149I23.6, IFIT1L

Description

Interferon-induced protein with tetratricopeptide repeats 1B (HGNC Symbol)

Entrez gene summary

Chromosome

10

Cytoband

q23.31

Chromosome location (bp)

89378056 - 89385205

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204010 (version 83.38)

Entrez gene

439996

UniProt

Q5T764 (UniProt - Evidence at transcript level)

neXtProt

NX_Q5T764

Antibodypedia

IFIT1B antibodies

PROTEIN BROWSER

IFIT1B-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IFIT1B-001
ENSP00000360874
ENST00000371809
Q5T764 [Direct mapping]
Interferon-induced protein with tetratricopeptide repeats 1B
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003723 [RNA binding]
GO:0005515 [protein binding]
GO:0005829 [cytosol]
GO:0051607 [defense response to virus]
GO:0060337 [type I interferon signaling pathway]
Show all
474 aa
55 kDa
No 0

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