Expression of IFIT1B in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

IFIT1B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	IFIT1B
Gene description	Interferon-induced protein with tetratricopeptide repeats 1B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (bone marrow, placenta)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Selective cytoplasmic expression in a subset of lymphoid cells.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA062924
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA062924

GENE INFORMATION
Gene name	IFIT1B (HGNC Symbol)
Synonyms	bA149I23.6, IFIT1L
Description	Interferon-induced protein with tetratricopeptide repeats 1B (HGNC Symbol)
Entrez gene summary
Chromosome	10
Cytoband	q23.31
Chromosome location (bp)	89378056 - 89385205
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204010 (version 83.38)
Entrez gene	439996
UniProt	Q5T764 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5T764
Antibodypedia	IFIT1B antibodies

PROTEIN BROWSER

IFIT1B-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
IFIT1B-001 ENSP00000360874 ENST00000371809	Q5T764 [Direct mapping] Interferon-induced protein with tetratricopeptide repeats 1B Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005829 [cytosol] GO:0051607 [defense response to virus] GO:0060337 [type I interferon signaling pathway] Show all	474 aa 55 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.